Citation Information :
Bansal R, Mittal N, Sankhla U, Gupta A, Dixit M. Laryngeal Herpes: Atypical Presentations. Int J Phonosurg Laryngol 2024; 14 (1):10-12.
Laryngeal herpes is a rare entity. Varicella zoster virus (VZV) can involve the pharyngolaryngeal region and cranial nerves. The first contact with this virus, transmitted by airborne particles shed from the skin of an infected person, produces symptoms. After resolution of symptoms, VZV travels to the dorsal root ganglia of the spinal cord, where it remains dormant for years. Reactivation of the virus occurs secondary to impaired cellular immunity. A case of a 60-year-old man presented with a change in voice and difficulty in swallowing. Another case of a 75-year-old woman presented with a change in voice, sore throat, and right facial palsy. In both cases, flexible laryngoscopy showed vesicles on the right side of the larynx. Cases were confirmed by laryngeal swab PCR testing. Both cases were treated with oral steroids and oral antiviral valacyclovir 500 mg three times a day for 10 days. This clinical condition should be kept in mind when a patient presents with unilateral sore throat and voice change.
Shinha T, Krishna P. Ramsay Hunt syndrome and zoster laryngitis with multiple cranial nerve involvement. IDCases 2015;2(2):47–48. DOI: 10.1016/j.idcr.2015.02.003
Gómez-Torres A, Medinilla Vallejo A, Abrante Jiménez A, et al. Ramsay-Hunt syndrome presenting laryngeal paralysis. Acta Otorrinolaringol Esp 2013;64(1):72–74. DOI: 10.1016/j.otorri.2011.08.003
Van Den Bossche P, Van Den Bossche K, Vanpoucke H. Laryngeal zoster with multiple cranial nerve palsies. Eur Arch Otorhinolaryngol 2008;265(3):365–367. DOI: 10.1007/s00405-007-0434-6
Pinto JA, Pinto HC, Ramalho Jda R. Laryngeal herpes: a case report. J Voice 2002;16(4):560–563. DOI: 10.1016/s0892-1997(02)00131-5
Choi JH. Two cases of pharyngolaryngeal zoster advanced to multiple cranial neuropathy. Am J Otolaryngol 2013;34(4):369–372. DOI: 10.1016/j.amjoto.2013.01.008
Lin YY, Kao CH, Wang CH. Varicella zoster virus infection of the pharynx and larynx with multiple cranial neuropathies. Laryngoscope 2011;121(8):1627–1630. DOI: 10.1002/lary.21859
Park JM, Kim SE, Yang HC. Clinical characteristics of herpes zoster laryngitis. Eur Arch Otorhinolaryngol 2020;277(10):2907–2912. DOI: 10.1007/s00405-020-06074-9
Nisa L, Landis BN, Giger R, et al. Pharyngolaryngeal involvement by varicella-zoster virus. J Voice 2013;27(5):636–641. DOI: 10.1016/j.jvoice.2013.02.011
Swain SK, Sahu MC, Behera IC. Management of Ramsay Hunt syndrome among HIV patients: our experience in a tertiary care hospital of eastern India. Pol Ann Med 2016;23:92–96. DOI: 10.1016/j.poamed.2016.01.013
Wu CL, Linne OC, Chiang CW. Herpes zoster laryngis with prelaryngeal skin erythema. Ann Otol Rhinol Laryngol 2004;113(2):113–114. DOI: 10.1177/000348940411300205
Yaguchi H, Hisatomi M, Sekine T, et al. Case of zoster sine herpete presenting with dysphagia diagnosed by PCR analysis of VZV DNA in auricular skin exudates. Rinsho Shinkeigaku 2006;46(9):668–670. PMID: 17260814.