International Journal of Phonosurgery & Laryngology

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VOLUME 9 , ISSUE 2 ( July-December, 2019 ) > List of Articles


Perceptual Recovery Effects of Thyme Drops after Vocal Loading for Professional Voice Users: A Randomized Placebo-controlled Single-blind Trial

Ben Barsties v Latoszek, Ewa v Latoszek

Keywords : Drops, Professional voice user, Thyme, Vocal health, Vocal loading

Citation Information : Barsties v Latoszek B, v Latoszek E. Perceptual Recovery Effects of Thyme Drops after Vocal Loading for Professional Voice Users: A Randomized Placebo-controlled Single-blind Trial. Int J Phonosurg Laryngol 2019; 9 (2):43-46.

DOI: 10.5005/jp-journals-10023-1173

License: CC BY-NC 4.0

Published Online: 01-12-2019

Copyright Statement:  Copyright © 2019; The Author(s).


Objective: The present study aimed to evaluate perceived recovery effects of drops after vocal loading. Particularly, thyme was evaluated, which has promising effects on the mucosa, throat, and airway system. Materials and methods: In total, 48 of 56 vocally healthy professional voice users were included because they presented with vocal fatigue after vocal loading. The subjects were randomized into two groups who received a thyme drop (TD), or a placebo drop (PD), after a 20-minute vocal loading task. The recovery effect by using drops was rated perceptually. Results: The results of the self-perceived rating showed higher significant outcomes for the TD group (p = 0.050 to p = 0.002). The TD group revealed a higher agreement for perceived well-being in the throat (i.e., 83.3%), a higher comfort in talking (i.e., 50.0%), and lower malaise/pain in the throat (58.3%) than the PD group (i.e., agreement of 50.0%, 16.7%, and 20.8%, respectively). Conclusion: Thyme drops might increase the comfort, well-being in the throat, and talking after vocal loading. Further research is necessary to investigate thyme and drops as potential benefit for professional voice users with high vocal loading.

  1. Bhattacharyya N. The prevalence of voice problems among adults in the United States. Laryngoscope 2014;124(10):2359–2362. DOI: 10.1002/lary.24740.
  2. Van Houtte E, Van Lierde K, D'Haeseleer E, et al. The prevalence of laryngeal pathology in a treatment-seeking population with dysphonia. Laryngoscope 2010;120(2):306–312.
  3. Mozzanica F, Ginocchio D, Barillari R, et al. Prevalence and Voice characteristics of laryngeal pathology in an Italian Voice Therapy-seeking population. J Voice 2016;30(6):774.e13–774.e21. DOI: 10.1016/j.jvoice.2015.11.018.
  4. Titze I, Lemke J, Montequin D. Populations in the U.S. Workforce who rely on voice as a primary tool of trade: a preliminary report. J Voice 1997;11(3):254–259. DOI: 10.1016/S0892-1997(97)80002-1.
  5. Vilkman E. Voice problems at work: a challenge for occupational safety and health arrangement. Folia Phoniatri Logop 2000; 52(1–3):120–125. DOI: 10.1159/000021519.
  6. Wingate JM, Brown WS, Shrivastav R, et al. Treatment outcomes for professional voice users. J Voice 2007;21(4):433–449. DOI: 10.1016/j.jvoice.2006.01.001.
  7. Ruben RJ. Redefining the survival of the fittest: communication disorders in the 21st century. Laryngoscope 2000;110(2 Pt 1):241–245. DOI: 10.1097/00005537-200002010-00010.
  8. Desjardins M, Halstead L, Cooke M, et al. A Systematic Review of Voice Therapy: What “Effectiveness” Really Implies. J Voice 2017;31(3):392.e13–392.e32. DOI: 10.1016/j.jvoice.2016.10.002.
  9. Friedrich G, Remacle M, Birchall M, et al. Defining phonosurgery: a proposal for classification and nomenclature by the Phonosurgery Committee of the European Laryngological Society (ELS). Eur Arch Otorhinolaryngol 2007;264(10):1191–1200. DOI: 10.1007/s00405-007-0333-x.
  10. Alves M, Krüger E, Pillay B, et al. The effect of hydration on voice quality in adults: a systematic review. J Voice 2019;33(1):125.e13–125.e28. DOI: 10.1016/j.jvoice.2017.10.001.
  11. Wagner L, Cramer H, Klose P, et al. Herbal medicine for cough: a systematic review and meta-analysis. Forsch Komplementmed 2015;22(6):359–368. DOI: 10.1159/000442111.
  12. Charalambous A, Lambrinou E, Katodritis N, et al. The effectiveness of thyme honey for the management of treatment-induced xerostomia in head and neck cancer patients: A feasibility randomized control trial. Eur J Oncol Nurs 2017;27:1–8. DOI: 10.1016/j.ejon.2017.01.001.
  13. Seibel J, Pergola C, Werz O, et al. Bronchipret® syrup containing thyme and ivy extracts suppresses bronchoalveolar inflammation and goblet cell hyperplasia in experimental bronchoalveolitis. Phytomedicine. 2015;22(13):1172–1177. DOI: 10.1016/j.phymed.2015.09.001.
  14. Seibel J, Kryshen K, Pongrácz JE, et al. In vivo and in vitro investigation of anti-inflammatory and mucus-regulatory activities of a fixed combination of thyme and primula extracts. Pulm Pharmacol Ther 2018;51:10–17. DOI: 10.1016/j.pupt.2018.04.009.
  15. Koufman JA, Isaacson G. The spectrum of vocal dysfunction. Otolaryngol Clin North Am 1991;24(5):985–988.
  16. Begrow F, Engelbertz J, Feistel B, et al. Impact of thymol in thyme extracts on their antispasmodic action and ciliary clearance. Planta Med 2010;76(4):311–318. DOI: 10.1055/s-0029-1186179.
  17. Salehi B, Mishra AP, Shukla I, et al. Thymol, thyme, and other plant sources: Health and potential uses. Phytother Res 2018;32(9): 1688–1706. DOI: 10.1002/ptr.6109.
  18. Verdolini Abbott K, Li NY, Branski RC, et al. Vocal exercise may attenuate acute vocal fold inflammation. J Voice 2012;26(6):814.e1–814.e13. DOI: 10.1016/j.jvoice.2012.03.008.
  19. Patel RR, Awan SN, Barkmeier-Kraemer J, et al. Recommended protocols for instrumental assessment of voice: american speech-language-hearing association expert panel to develop a protocol for instrumental assessment of vocal function. Am J Speech Lang Pathol 2018;27(3):887–905. DOI: 10.1044/2018_AJSLP-17-0009.
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