International Journal of Phonosurgery & Laryngology

Register      Login

VOLUME 5 , ISSUE 2 ( July-December, 2015 ) > List of Articles

RESEARCH ARTICLE

Atypical Presentations of Laryngeal Cancers: Diagnostic and Treatment Dilemmas

Jyoti Dabholkar, Neeti Madan Kapre, Ameya Bihani

Citation Information : Dabholkar J, Kapre NM, Bihani A. Atypical Presentations of Laryngeal Cancers: Diagnostic and Treatment Dilemmas. Int J Phonosurg Laryngol 2015; 5 (2):53-56.

DOI: 10.5005/jp-journals-10023-1105

Published Online: 00-12-2015

Copyright Statement:  Copyright © 2015; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Introduction

Larynx is a complex organ with various subsites and a myriad of pathologies. Atypical presentations of laryngeal cancers are rare with literature only in the form of case reports or series with small number of patients.

Aim of study

It is important to recognize rare presentations of laryngeal carcinomas in order to pre-empt misdiagnosis and execute an appropriate treatment plan.

Materials and methods

We present a case series of four such atypical presentations which were managed with precise and individualized approaches.

Results

Three patients with rare manifestations of laryngeal squamous cancers were treated surgically in view of gross exolaryngeal spread. Single case of melanoma was treated with chemoradiation followed by surgical salvage.

Conclusion

All four patients were identified through adequate diagnostic precision on part of the clinician.

Clinical implications

The form and function of the larynx are crucial to the quality of life of a patient. Laryngeal carcinomas require appropriate treatment approach to ensure the same. The clinician needs to be aware of these atypical presentations as well in order to diagnose and treat these patients effectively.

How to cite this article

Dabholkar J, Kapre NM, Bihani A. Atypical Presentations of Laryngeal Cancers: Diagnostic and Treatment Dilemmas. Int J Phonosurg Laryngol 2015;5(2):53-56.


PDF Share
  1. Atypical laryngeal lesions-problems in diagnosis. Calif Med 1954 Nov;81(5):328-331.
  2. Differential diagnosis of laryngeal spindle cell carcinoma and inflammatory myofibroblastic tumor—report of two cases with similar morphology. Diagnostic Pathol 2007 Jan;2:1.
  3. A spindle cell carcinoma presenting with osseous metaplasia in the gingiva: a case report with immunohistochemical analysis. Head Face Med 2008 Dec 1;4:28.
  4. Spindle cell (sarcomatoid) carcinomas of the larynx: a clinicopathologic study of 187 cases. Am J Surg Pathol 2002 Feb;26(2):153-170.
  5. Collision tumour of the thyroid: follicular carcinoma plus papillary carcinoma plus adenomatous goitre. World J Med Surg 2013;4(2):5.
  6. Cricoid chondrosarcoma coexisting with a thyroid mass: case report and review of the literature. Tumori 2006 May-Jun;92(3):257-259.
  7. Current management of mucosal melanoma of the head and neck. J Surg Oncol 2003 Jun;83(2):116-122.
  8. Mucosal melanomas of the head and neck. Head Neck Surg 1978 Sep-Oct;1(1):24-30.
  9. Subglottic presentation of a rare tumor: primary or metastatic? Primary mucosal melanoma of the subglottic larynx. JAMA Otolaryngol Head Neck Surg 2013 Jul;139(7):739-740.
  10. Collision tumor of primary laryngeal mucosal melanoma and invasive squamous cell carcinoma with IL-17A and CD70 gene over-expression. Head Neck Pathol 2010 Dec;4(4):295-299.
  11. Malignant melanoma: a clinicopathological analysis of the criteria for diagnosis and prognosis. Cancer 1953 Jan;6(1):1-45.
  12. Mucosal melanomas of the head and neck: the role of postoperative radiation therapy. ISRN Oncol 2012;2012:785131.
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.