International Journal of Phonosurgery & Laryngology

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VOLUME 12 , ISSUE 1 ( January-June, 2022 ) > List of Articles


Injection Laryngoplasty with Hyaluronic Acid: A Study to Analyze the Quality and Longevity of Voice Improvement in Unilateral Vocal Cord Palsy

Gopishankar Subramaniasamy, Anagha Atul Joshi, Pushkaraj Kulkarni, Renuka A Bradoo, Madhu S Velecharla

Keywords : Hyaluronic acid, Injection laryngoplasty, Techniques of injection laryngoplasty, Vocal cord palsy, Voice improvement

Citation Information : Subramaniasamy G, Joshi AA, Kulkarni P, Bradoo RA, Velecharla MS. Injection Laryngoplasty with Hyaluronic Acid: A Study to Analyze the Quality and Longevity of Voice Improvement in Unilateral Vocal Cord Palsy. Int J Phonosurg Laryngol 2022; 12 (1):22-30.

DOI: 10.5005/jp-journals-10023-1231

License: CC BY-NC 4.0

Published Online: 30-07-2022

Copyright Statement:  Copyright © 2022; The Author(s).


Purpose: To study the efficacy of injection laryngoplasty with hyaluronic acid in unilateral vocal cord palsy with respect to the quality of voice, symptomatic relief, and longevity of treatment outcome. Materials and methods: A prospective study was conducted, including 20 patients with unilateral vocal cord palsy. Injection laryngoplasty with hyaluronic acid was done as an office-based procedure by different approaches. Patients were assessed before the procedure and at regular intervals for 6 months after the procedure using various voice parameters, viz. GRBAS scale, maximum phonatory time, voice handicap index, and voice analysis by Dr. Speech voice analyzer software. Laryngoscopy was also done at each follow-up to check for the phonatory gap. Results: Injection laryngoplasty with hyaluronic acid was done successfully in all 20 patients with complete glottal closure. The thyrohyoid percutaneous technique was the most preferred approach. All voice parameters showed statistically significant improvement for 6 months. The phonatory gap closure was almost maintained throughout the period of 6 months, with none having symptoms of aspiration. No side effects were noted in our study. Conclusion: Injection laryngoplasty with hyaluronic acid is an effective temporary treatment modality in cases of unilateral vocal cord palsy, which can give good quality of voice and overcome aspiration for at least a period of 6 months.

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